The Southeast Regional Collaborative Access Team (SER-CAT) is an organization consisting of 22 Member and 5 Associate User institutions, formed in 1997 to provide third generation x-ray capabilities to macromolecular crystallographers and structural biologists in the southeastern region of the U.S.
Emphasis is placed on de novo SAD/MAD structure determination, high-resolution structural analyses, large unit cells, drug design, structural genomics, soft X-ray data collection and next-generation beamline automation. SER-CAT is located at the Advanced Photon Source, Argonne National Laboratory, and is operated by the University of Georgia, with Professor Bi-Cheng Wang as Director.
Please peruse the pages of our website to find out more about SER-CAT and how we are "shining a new light" on protein crystallography. Have a look at The SER-CAT Spectrum, our newsletter, to learn about recent breakthroughs. As always, your comments and suggestions are welcome.
Thank you for visiting!
*News and Announcements*
15th Annual SER-CAT Symposium
The 15th Annual SER-CAT Symposium will be held
on Friday April 13, 2018 at the Georgia Institute of Technology. The
Annual Board Meeting will be held on Saturday, April 14.
SER-CAT Detector Workshop
A workshop on the "Best Practices for the Collection, Processing, Analysis, Transfer & Storage of data from the new Eiger 16M detector" will
be held on April 12th preceeding the SER-CAT Symposium. The
workshop is free for SER-CAT Symposium registrants.
14th Annual SER-CAT Symposium
The 14th Annual SER-CAT Symposium was held on April 7, 2017 on the Scripps Research Institute – Florida Campus. The meeting featured talks related to the APS upgrade, highlights of scientific advances enabled by SER-CAT data, new user tools available at SER-CAT and the presentation SER-CAT Young Investigator and Outstanding Awards. A posted session followed.
Dr. Stephen Streiffer, the ANL Associate Laboratory Director for Photon Sciences presented current plans for upcoming APS upgrade followed a discussion with the meeting participants on the upgrade will impact SER-CAT capabilities and support new science.
Meeting participants discussed outstanding research projects conducted at SER-CAT throughout the year. SER-CAT beamline scientists shared the beamline advances including new sector specific hardware and software, and data collection features. SER-CAT director Dr. Bi-Cheng Wang presented the “SER-CAT Pilot Project: Phase II – Extending the concept of color photography to routine chromatic X-ray Crystallography”.
SER-CAT sincerely thanks the Symposium's organizing committee Dr. Tina Izard, Ms. Candace Morrow and the staff at the Scripps Research Institute – Florida Campus for planning and organizing this year's informative and very enjoyable event. Our sincere thanks to all speakers and participants for making this year's symposium such a successful event.
SER-CAT 2017 Award Winners
2017 SER-CAT Young Investigator Award was presented to Mr. William
Bradley O’Dell, North Carolina State University, by Dr. B.C. Wang for
his researchon “Oxygen
activation by a lytic polysaccharide monooxygenase”.
Special thanks to all of the nominators for this year's Awards.
Associate User Memberships Available
Associate User memberships are now available on a yearly basis with no capital; investment or long-term contractual commitment. Associate memberships are available to both academic and industrial users and provide full access to SER-CAT's outstanding Remote Access program at an attractive cost.
For more information, please contact SER-CAT Program Coordinator, Ms. Zhi-Qui (Lily) Li at email@example.com.
Eiger 16M Detector Installed on 22ID
new Dectris Eiger 16M detector has been commissioned at 50 Hz and is
available to users on beamline 22ID. The Eiger is a hybrid photon
counter that has a pixel size comparable to that of the Rayonix MX300HS
but can collect data up to ten times faster (100 Hz). In addition,
unlike the MX300HS, the Eiger has a very high dynamic range reducing
saturation problems. When coupled with the new KB mirrors being
installed on 22ID the beamline should be ideal for
microcrystallography. The Rayonix MX300HS
detector will be moved to beamline 22BM significantly increasing data
rate and data quality.
A workshop on "Best Practices for the Collection, Processing, Analysis, Transfer and Storage of Data from the New SER-CAT Eiger 16M Detector" will be offered on April 12, 2018 (one day before the SER-CAT Symposium) at the Georgia Institute of Technology.
SER-CAT welcomes Dr. Norma Duke who will be replacing Gina Ranieri in April. Dr. Duke joins us from SBC CAT where she was a Beamline support Specialist/Macromolecular Crystallographer. She will assume most of Gina's duties, as well as provide User Support.
SER-CAT welcomes Michael Molitsky, Mike as SER-CAT Senior Beamline Engineer will assume John Gonczy’s duties related to beamline matters. Mike was the Principal Beamline Scientist at SBC-CAT from 2004 to 2016 and also was responsible for optic and hardware improvements.
SER-CAT welcomes Lily Li and Jackie Taylor who will be joining the Administrative Office at UGA. Lily has been with us since 1996 and has been promoted to SER-CAT Program Coordinator where she will assume the most of Kathy Savage's outreach and administrative duties while Jackie will serve as the SER-CAT Administrative Specialist assuming Kathy's accounting duties.
SER-CAT bids a fond farewell to John Gonczy, Kathy Savage and Gina Ranieri. John was part of the SER-CAT construction team and served as Beamline Engineer and User Support since 2002. He has retired after 20 years service. Kathy has served as the SER-CAT Administrative Coordinator and played an important role in the establishment, and success of SER-CAT. She is retiring after 30 years' service to UGA. Gina our User Support Coordinator has left us to pursue a career at Procter & Gamble. SER-CAT wishes Gina all success in her new career.
Rayonix MX300HS Users Guide
A data collection guide for the MX300HS has been prepared and can downloaded by clicking the link below.
Please look it over since there are several changes in what you will need to do to collect data and process data with the new detector.
for the MX300HS
for the MX300HS
A new version of HKL2000 that can process the data from
the MX300HS detector is available for download from HKL Research.
Please contact them for download instructions. You will alos need
to get an updated cr_info file.
A new version of HKL2000 that can process the data from the MX300HS detector is available for download from HKL Research. Please contact them for download instructions. You will alos need to get an updated cr_info file.
Both BM and ID Robots are fully commissioned. All first time
robotics users must contact Norma Duke (SER-CAT's User Support Coordinator) prior to their visit.
Firewire Disk Drives
SER-CAT'S 20th Anniversary
2017 marks SER-CAT's 20th year of operation. We have put together a slide show (below) highlighting SER-CAT's early history which B.C. Wang presented at the Scripps-Flordia SER-CAT Symposium.
SER-CAT: The first 10 years